You are here
Home > Biology

Download Aminoacyl-tRNA Synthetases in Biology and Medicine by Sunghoon Kim PDF

By Sunghoon Kim

ISBN-10: 940178700X

ISBN-13: 9789401787000

This publication will concentrate on new molecular interactions and novel actions and the linked illnesses which were lately came upon from the reports of eukaryotic and mammalian aminoacyl-tRNA synthetases. furthermore, the capability functions of ARS researches in biotechnology and drugs may be addressed.

Show description

Read or Download Aminoacyl-tRNA Synthetases in Biology and Medicine PDF

Similar biology books

Charge Migration in DNA: Perspectives from Physics, Chemistry, and Biology

Cost migration via DNA has been the focal point of substantial curiosity in recent times. A deeper realizing of the character of cost move and delivery alongside the double helix is necessary in fields as diversified as physics, chemistry and nanotechnology. It has additionally vital implications in biology, particularly in DNA harm and service.

The Molecular Biology of Cyanobacteria

Greater than two decades in the past, as a fledgling graduate a few atypical features of the genetics of those pupil who was once simply beginning to find out about those organisms yet to pay respects to the 2 volumes of organisms that may develop into my basic learn Carr of Whitton that performed vital roles in my concentration, the e-book of Noel Carr and Brian personal puzzling over cyanobacteria (and doubtless in Whitton's The Biology of the Blue-Green Algae within the improvement of many others as well).

Additional resources for Aminoacyl-tRNA Synthetases in Biology and Medicine

Sample text

Cusack S (1997) Aminoacyl-tRNA synthetases. Curr Opin Struct Biol 7:881–889 37. Guo M, Schimmel P (2012) Structural analyses clarify the complex control of mistranslation by tRNA synthetases. Curr Opin Struct Biol 22:119–126 38. Tang SN, Huang JF (2005) Evolution of different oligomeric glycyl-tRNA synthetases. J. Perona and I. Gruic-Sovulj 39. Dock-Bregeon A, Sankaranarayanan R, Romby P, Caillet J, Springer M, Rees B, Francklyn CS, Ehresmann C, Moras D (2000) Transfer RNA-mediated editing in threonyl-tRNA synthetase.

Therefore, among all editing aaRS, IleRS may be unique with respect to this property [8, 47]. Further detailed structure–function studies of IleRS are needed to understand how tRNA enhancement of pre-transfer editing functions. An earlier model for tRNA-dependent pre-transfer editing, developed for editing of valine by IleRS, invoked a complex mechanism by which noncognate aminoacyl adenylates are shuttled to the CP1 domain editing site, so that this active site would catalyze both pre-transfer and post-transfer editing [182–185].

Structure 3:17–31 100. Eriani G, Delarue M, Poch O, Gangloff J, Moras D (1990) Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs. Nature 347:203–206 101. Cavarelli J, Eriani G, Rees B, Ruff M, Boeglin M, Mitschler A, Martin F, Gangloff J, Thierry JC, Moras D (1994) The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction. EMBO J 13:327–337 102. Dignam JD, Guo J, Griffith WP, Garbett NC, Holloway A, Mueser T (2011) Allosteric interaction of nucleotides and tRNA(ala) with E.

Download PDF sample

Rated 4.19 of 5 – based on 36 votes